Publications by authors named "R V Golubev"

This work focuses on the first use of ultrasonic phenol-ene coupling as a polymer analogous transformation. The ultrasonic reaction was introduced into chitin chemistry, resulting in the fast and convenient preparation of new water-soluble cationic chitin derivatives. Since water-soluble derivatives of fully deacetylated chitin are poorly described in the literature, the synthesis of each new type of these derivatives is a significant event in polysaccharide chemistry.

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Article Synopsis
  • The study focused on creating and evaluating chitosan-based films that contain Rhodamine B, assessing their mechanical, photophysical, and antibacterial properties.
  • These films were produced via a casting method, with their mechanical attributes influenced by the chemical composition and drying techniques used.
  • The results indicated that these films not only have enhanced antibacterial activity but also show potential as fluorescent temperature sensors, making them applicable in areas like healthcare, food safety, and agriculture.
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Ciprofloxacin is one of the most effective antibiotics, but it is characterized by a range of side effects. Elaboration of drug-releasing systems which allow to diminish toxicity of ciprofloxacin is a challenging task in medicinal chemistry. The current study is focused on development of new ciprofloxacin releasing systems (CRS).

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The objective of the present study was the development of the methods for the isolation and identification of pregabalin for the purpose of chemical toxicological analysis (CTA). The authors describe the methods used to obtain pregabalin from the model mixtures of urine and blood plasma with the use of liquid-liquid and solid phase extraction. In addition, a method for the quantitative determination of pregabalin by means of combined gas chromatography mass-spectrometry was applied.

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Aim: To assess the results of determination of glycation end-products (GEPs) by skin autofluorescence (AF) in patients on chronic hemodialysis (HD).

Subjects And Methods: A device made in Russia was used to estimate skin AF intensity in 40 apparently healthy individuals and in 76 patients treated with chronic HD. While analyzing the findings, comparisons were made in both groups; a relationship between skin AF intensity and clinical and laboratory parameters was also investigated in patients on HD.

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