Publications by authors named "R V DeMars"
Monoclonal antibodies that bind to human leukocyte antigen (HLA) are useful tools for HLA-typing, tracking donor-recipient chimerisms after bone marrow transplants, and characterizing specific major histocompatibility complexes (MHC) on cell surfaces. Unfortunately, equivalent reagents are not available for rhesus macaques, which are commonly used animal as models in organ transplant and infectious disease research. To address this deficiency, we isolated an antibody that recognizes the common Indian rhesus macaque MHC class I molecule, Mamu-A1*001.
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- A cohort study focused on women treated for skin hemangioma with ionizing radiation in early childhood, aiming to investigate its link to breast cancer incidence.
- During an average follow-up of 35 years, 17 women diagnosed with invasive breast cancer were identified, showing a higher incidence than expected in the general population.
- The study concluded that previous radiation treatment for hemangioma in childhood increases the risk of developing breast cancer later in life, particularly with higher radiation exposure.
The high frequency of between-strain genetic recombinants of Chlamydia trachomatis among isolates obtained from human sexually transmitted infections suggests that lateral gene transfer (LGT) is an important means by which C. trachomatis generates variants that have enhanced relative fitness. A mechanism for LGT in C.
View Article and Find Full Text PDFGenetic recombinants that resulted from lateral gene transfer (LGT) have been detected in sexually transmitted disease isolates of Chlamydia trachomatis, but a mechanism for LGT in C. trachomatis has not been described. We describe here a system that readily detects C.
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