Publications by authors named "R Urbanek"

Article Synopsis
  • The MedPed project investigated familial hypercholesterolemia cases and discovered a patient with extremely low levels of total and LDL-cholesterol in her sister, suggesting a rare condition.
  • This led to a suspicion of Tangier disease, a genetic disorder that results in nearly absent HDL-cholesterol and low apolipoprotein A-I, confirmed by genetic testing.
  • The study highlights the first documented case of homozygous Tangier disease in the Czech Republic, originally identified in 1961 on Tangier Island.
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In the conservation of endangered species, suppression of a population of one native species to benefit another poses challenges. Examples include predator control and nest parasite reduction. Less obvious is the control of blood-feeding arthropods.

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Background And Aims: Despite the high prevalence of familial hypercholesterolemia (FH) and available effective lipid-lowering therapy, most of the individuals with this disorder remain undiagnosed and undertreated. The aim of the PLANET registry was to assess the real-life attainment of low-density lipoprotein cholesterol (LDL-C) therapeutic target level in patients with heterozygous FH, to characterize prescribed lipid-lowering therapy with assessment of its efficiency according to the attainment of the target LDL-C level, and to characterize cardiovascular events observed in this patient population again in relation to LDL-C target level attainment.

Methods: PLANET registry was designed as a non-interventional, retrospective, cross-sectional, multicentre disease registry for adult patients with heterozygous FH in the Czech Republic and Slovakia.

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State parks serve an important dual role in conservation by balancing wildlife management and recreation activities by park visitors. However, research in recreation ecology on the collective impacts of non-consumptive recreation, environmental factors, and trail design has been sparse. We modeled the influences of non-consumptive trail use, vegetation communities, habitat structure, climate, and trail design on avian communities in four Arkansas State parks.

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A 56-year-old man presented with a 15-year history of scaly red plaques on the trunk and axillae. Skin biopsy was consistent with Hailey-Hailey disease. His condition was refractory to multiple therapies, which included topical and oral antibiotics and topical, intralesional, and oral glucocorticoids.

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