[Intercellular interactions during the healing of an experimental skin wound].

On the model of skin wound in white rats in the dynamics of wound process the interaction of mast cells and fibroblasts was studied. Quantitative, morphological and functional changes of mast cells, the content of free and total histamine and serotonin, the reaction of fibroblasts in the focus of skin lesion during 20 days after injury were investigated. It was established that the mast cells played an important role not only in the early inflammatory phase but also in the later time of wound process.

[Mast cells of the lungs in experimental hyperergic pleurisy].

Reaction of mast cells, the content of free and cell histamine and serotonin in the lung tissue at early stage of inflammation were studied on the model of hyperergic pleurisy in albino rats. Intrapleural antigen injection to sensitized rats was followed by progressive degranulation of mast cells of pleural and subpleural lung tissue with release of histamine and serotonin. The maximal increase in the content of free amines was found after 15 min.

[Cholinergic processes as affected by small doses of radiation on the host].

Acetylcholine content of blood and cholinesterase activity in blood and tissues of albino rats were studied at different time-intervals after gamma-irradiation with doses of 12.9 and 25.8 mC/kg.