Leveraging Explainable AI for Early Risk Prediction and Type Classification for Leukemia: Insights using Clinical Data from Pakistan.

Leukemia, a prevalent childhood cancer affecting the blood and bone marrow, necessitates a proactive approach to risk mitigation through lifestyle adaptations. Despite previous investigations into similar aspects across different cancer types, a comprehensive inquiry focusing on all leukemia subtypes within Pakistan remains a significant research gap. Acknowledging the influence of regional variations on individuals' lifestyles, this study aims to identify lifestyle and demographic factors associated with leukemia development and predict specific leukemia subtypes using clinical data.

Association between Socioeconomic Inequality and the Burden of Colon and Rectum Cancer in Asia: GLOBOCAN Sources and Methods.

Introduction: Colon cancer is the third most common malignancy worldwide, which is increasing in middle-income countries. Our aim in this study was to investigate the association between socioeconomic inequality and the burden of Colon and rectum cancer in Asia.

Methods: All accessible data sources from 1990 to 2019 Global Burden of Disease study were used to estimate the prevalence, mortality, and disability-adjusted life years and the burden of Colon and rectum cancer in Asia.

Recurrent Missense Driver STAT5B N642H Mutation in Children Transiting into Adolescence, with Acute Lymphoid Leukemia and its In silico Inhibition.

Background: The occurrence of gain of function mutations in STAT5B has been associated to survival, and drug resistance in Leukemia. In silico screening of compounds having inhibitory potential towards mutated proteins, can be helpful in the development of specific inhibitors.

Objective: This study was designed to screen selected JAK-STAT mutations in leukemia patients and virtual exploration of molecular interaction of potential inhibitors with their mutated products.

Serosurvey of Toxocariasis and Its Association With Allergic Asthma in Children: A Case-Control Study in Southwest Iran.

Evidence from multiple data sources indicates that toxocariasis might play a role in the allergic asthma in children. This case-control study investigated the connection between Toxocara seropositivity and allergic asthma. It also sought to identify the conventional risk factors associated with both asthma and Toxocara infection.

A Bibliometric Analysis on Urticaria: Roles of Oxidative Stress, Inflammation, Immunity, and Treatment Modalities.

This study provides a comprehensive bibliometric analysis of global research on urticaria, aiming to chart its progression, assess its relevance, and explore the roles of oxidative stress, inflammation, and immunity in its pathogenesis. Additionally, by analyzing data from PubMed and Scopus, we mapped research trends, identified leading authors and institutions, and examined global collaboration patterns. We also evaluated the impact of oxidative stress, inflammation, and immunity on urticaria and assessed the roles of both conventional and traditional medicine in its management.