A survey of foundation dentists' experiences of clinical audit.

Introduction Clinical audit is one of the central pillars of clinical governance and is a valuable quality improvement tool. Clinical audit has benefits for all stakeholders and provides evidence of compliance with the requirements of the UK statutory regulatory bodies. The levels of knowledge, experience and understanding of clinical audit of recent UK graduates is variable.

Conjugates of amiridine and salicylic derivatives as promising multifunctional CNS agents for potential treatment of Alzheimer's disease.

New conjugates of amiridine and salicylic derivatives (salicylamide, salicylimine, and salicylamine) with different lengths of alkylene spacers were designed, synthesized, and evaluated as potential multifunctional central nervous system therapeutic agents for Alzheimer's disease (AD). Conjugates demonstrated high acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition (IC: AChE, 0.265-4.

Manipulating button mushroom casing affects the disease dynamics of blotch and green mold disease.

Productive cultivation of the button mushroom (Agaricus bisporus) relies on the use of selective substrates and effective disease management. In extending our previous work on manipulating the developmental microbiome (devome), this study employs the strategy of substrate passaging to explore its effects on crop outcomes and disease dynamics. Here we subjected the casing substrate to ten cycles of passaging.

Principles of Stereotactic Surgery.

Background And Objectives: Stereotactic procedures are used to manage a diverse set of patients across a variety of clinical contexts. The stereotactic devices and software used in these procedures vary between surgeons, but the fundamental principles that constitute safe and accurate execution do not. The aim of this work is to describe these principles to equip readers with a generalizable knowledge base to execute and understand stereotactic procedures.