Publications by authors named "R Tuma"
Transcription factors of the bHLH-PAS family play vital roles in animal development, physiology, and disease. Two members of the family require binding of low-molecular weight ligands for their activity: the vertebrate aryl hydrocarbon receptor (AHR) and the insect juvenile hormone receptor (JHR). In the fly Drosophila melanogaster, the paralogous proteins GCE and MET constitute the ligand-binding component of JHR complexes.
View Article and Find Full Text PDFNatural rubber latex membrane (NRL) is a biocompatible macromolecule that stimulates angiogenesis and promotes bone repair. Similarly, β-tricalcium phosphate (β-TCP) is an osteoconductive and osteoinductive bioceramic widely used as a bone substitute. Here, we investigated the combined use of these biomaterials in the guided bone regeneration process for calvarial defects in rats.
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- A study investigated the use of the middle cerebral artery pulsatility index (MCA-PI) to predict adverse outcomes in pregnancies affected by idiopathic polyhydramnios, which is an abnormal excess of amniotic fluid.
- The research included 128 pregnancies with idiopathic polyhydramnios, revealing that those with MCA-PI below the 10th percentile had significantly higher rates of emergency cesarean deliveries (25.9% vs. 7.9%) and adverse perinatal outcomes (37.0% vs. 15.8%).
- The findings suggest that a lower MCA-PI may indicate fetal distress and increased risk for neonatal complications, though cerebroplacental ratio values did not correlate with adverse outcomes