Successful treatment of esophageal perforation due to black esophagus (acute esophageal necrosis): a case report.

Background: Black esophagus, or acute esophageal necrosis (AEN), is a rare disease with a poor prognosis in which the esophageal mucosa is black in color. We report a case of esophageal perforation due to AEN that was successfully treated.

Case Presentation: An 88-year-old woman presented to her local hospital with the chief complaint of abdominal pain.

Impact of inhaled ciclesonide on asymptomatic or mild COVID-19: A randomized trial.

The aim of this study was to determine the efficacy and safety of ciclesonide in the treatment of novel coronavirus disease 2019 (COVID-19) as gauged by pneumonia progression. This multi-center, open-label randomized trial was conducted with patients recruited from 22 hospitals across Japan. Participants were patients admitted with mild or asymptomatic COVID-19 without signs of pneumonia on chest X-rays.

Mutations Found in the Gene That Confer Susceptibility to the AAL-Toxin in Ancestral Tomatoes from Peru and Mexico.

Tomato susceptibility/resistance to stem canker disease caused by f. sp. and its pathogenic factor AAL-toxin is determined by the presence of the gene.