Publications by authors named "R Trisolini"

Diagnosing non-tuberculous mycobacterial pulmonary disease (NTM-PD) in patients unable to produce sputum spontaneously requires invasive procedures to obtain valid respiratory specimens. In this retrospective study, we evaluated the results of microbiological tests performed on respiratory samples of 132 patients affected by NTM-PD. In the diagnostic workout, 98 patients performed both induced sputum (IS) and bronchoalveolar lavage (BAL) and were enrolled in our study.

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While recent randomized controlled trials (RCT) have suggested superior overall survival (OS) outcomes with segmentectomy over lobectomy, questions remain regarding the comparability of these surgical procedures for treating early-stage non-small cell lung cancer (NSCLC). This systematic review and meta-analysis aimed to synthetize existing evidence and to compare the survival outcomes observed for stage IA NSCLC following segmentectomy or lobectomy. 40 studies (38 observational, 2 RCTs) encompassing 103,926 patients were analyzed.

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Article Synopsis
  • The ongoing FPG500 program aims to provide personalized targeted therapies for non-small cell lung cancer (NSCLC) based on genetic profiling, assessing patient eligibility through comprehensive genome profiling (CGP).
  • In 2022, a significant study involving 283 NSCLC patients revealed that 93% were eligible for sequencing, with 76% undergoing high-throughput genomic analysis, leading to the identification of potential driver mutations in 59% of them.
  • Results showed varying progression-free survival (PFS) and overall survival (OS) rates dependent on the type of treatment received, emphasizing the benefits of implementing CGP and molecular tumor board evaluations in improving patient outcomes.
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The use and availability of diverse advanced X-ray based imaging and guidance systems in the field of interventional pulmonology are rapidly growing. This popularity links inextricably to an increase in ionizing radiation use. Knowing ionizing radiation is hazardous, knowledge and competent use of X-ray imaging and guidance systems are important.

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