[Serological evaluation of an antimeningococcal mass vaccination campaign in Niger].

Authors searched by mean of radio-immuno-essay A and C anti-meningococcal antibodies in two villages from Niger (181 and 92 patients) in a meningitidis endemic area, which one profited 10 months ago of a mass vaccination campaign (A and C polysaccharides). A and C antibodies quantities and percentages of protected patients are not significantly different between the two villages. In one hand anti-C levels increase with patients age.

[20 years' use of the diphtheria-pertussis-tetanus vaccine].

Between 1966 and 1982, a triple DPT vaccine was studied in France in 1,871 infants between the ages of 3 and 5 months. The study covered tolerance and serological efficacy of two immunization schedules using 2 or 3 initial injections. Computerized analysis of the 877 complete files showed satisfactory tolerance of this association and the serological efficacy of 2 initial doses of tetanus and diphtheria vaccines.

Antibodies to meningococcus polysaccharides in nonspecific gamma-globulins from different regions of the world.

Seventy-one batches of nonspecific gamma-globulin obtained from France, USSR and Mongolia were studied for presence of specific antibody to group A and C meningococcus polysaccharide. Specific activity was tested by two methods: radioimmunoassay (Lyon) and reaction of passive haemagglutination inhibition (Moscow). Antibodies were detected in all the gamma-globulin batches tested, in some of them at high titres.