Publications by authors named "R Totaro"
Background: Gender differences in the access to advanced therapies for Parkinson's disease (PD) are poorly investigated.
Objective: The objective of this study was to investigate the presence of any gender disparity in the access to advanced therapies for PD.
Design: Retrospective study.
Neutrophil count as a risk factor for cardiovascular diseases: how can we manage it?
J Cardiovasc Med (Hagerstown)
November 2024
Neutrophils activation plays a pivotal role in the pathogenesis of atherosclerotic plaque formation, progression and rupture. An association between the leukocyte count and the risk of developing myocardial infarction has been well known for many years; however, only recently did Mendelian randomization studies show that a high neutrophil count is a causal risk factor for atherosclerotic cardiovascular disease. On the other hand, experimental studies show that depletion of circulating neutrophils impairs plaque development.
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- * Traditional antidepressants can cause unwanted side effects like weight gain and sexual dysfunction, making them less suitable for some MS patients.
- * Vortioxetine, a new antidepressant with a unique mechanism, may improve symptoms of depression and anxiety in MS patients and could have additional benefits due to its possible anti-inflammatory properties; however, more specific research on its effectiveness in MS is needed.