Publications by authors named "R Torne"
Purpose: Spine biomechanics, particularly sagittal balance and spino-pelvic angulation are determinant factors in the understanding of lumbar degenerative disease. These concepts translated into objective measurements are progressively being integrated into clinical practice. The present study explores them as prognostic factors in patients undergoing lumbar microdiscectomy, which could help identify those at higher risk of surgical failure.
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- The study investigates the transorbital approach (TO) for accessing vascular lesions, specifically the carotid and middle cerebral arteries, using cadaveric specimens to understand its feasibility for vascular clipping.
- Dissection involved a stepwise TO method that included procedures like lateral orbital craniectomy and anterior clinoidectomy, allowing for exposure of various vascular segments and cranial nerves.
- Findings suggest that the TO approach effectively exposes key artery segments, indicating its potential use in treating paraclinoid and posterior communicating aneurysms.
Background And Objectives: The major clinical implication of brain arteriovenous malformations (bAVMs) is spontaneous intracranial hemorrhage. There is a growing body of experimental evidence proving that inflammation and blood-brain barrier (BBB) dysfunction are involved in both the clinical course of the disease and the risk of bleeding. However, how bAVM treatment affects perilesional BBB disturbances is yet unclear.
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- Researchers in Spain studied a serious brain condition called spontaneous subarachnoid hemorrhage (SAH) over two years to see how often it happens, how it affects people, and how many survive.
- They looked at data from 550 patients, finding that about 21% died in the hospital and 27% within a year, but many did well after treatment.
- The study revealed that men tended to be younger and that those living in rural areas took longer to get to the hospital; it showed that improvements in treatment are needed to reduce deaths, especially in specific populations.
Objective: Ischemic complications account for significant patient morbidity following aneurysmal subarachnoid hemorrhage (aSAH). The Prevention and Treatment of Vasospasm with Clazosentan (REACT) study was designed to assess the safety and efficacy of clazosentan, an endothelin receptor antagonist, in preventing clinical deterioration due to delayed cerebral ischemia (DCI) in patients with aSAH.
Methods: REACT was a prospective, multicenter, randomized, double-blind, phase 3 study.