Increasing the Working Time of Forging Tools Used in the Industrial Process of Producing a Disk-Type Forging Assigned for a Gearbox through the Application of Hybrid Layers.

The article discusses the phenomena and destructive mechanisms occurring on the surface of 1.2344 steel dies used during the hot forging of disc-type forgings. Preliminary research has shown that gas nitriding alone, used so far, is insufficient due to the occurrence of destructive mechanisms other than abrasive wear, such as thermal and thermomechanical fatigue, which cause the average durability of such tools to be approximately 5000 forgings.

Serum lipoprotein changes in female rats treated with progesterone or synthetic gestagens alone or in combination with estradiol. II. Serum triglycerides and hepatic triglyceride release.

The influence of progesterone (P) and synthetic gestagens given alone or in combination with estradiol (E2) on triglyceride (TG) concentration in serum of adult female rats was studied. Norethisterone acetate (NEA), levonorgestrel (LNG), dienogest (DEG), chlormadinone acetate (CMA) and P were administered orally at a dose of 10 mg/kg for three times. E2 was given chronically by s.

Serum lipoprotein changes in female rats treated with progesterone or synthetic gestagens alone or in combination with estradiol. I. Total and fractionated cholesterol and lipoprotein pattern.

In adult female rats, the effects of progesterone (P), norethisterone acetate (NEA), levonorgestrel (LNG), dienogest (DEG) and chlormadinone acetate (CMA) given alone at doses of 2.5 or 10 mg/kg p.o.

Interactions between progestins and estradiol on serum lipids in the rat.

In female rats the influence of progestins of the estrane type [norethisterone acetate (NEA), norgestrel (NG) and dienogest (DEG)] and of the pregnane type [chlormadinone acetate (CMA), progesterone (P)] on total cholesterol (TC) and high-density-lipoprotein cholesterol (HDL-C) in serum has been investigated in combination with estradiol (E). E increased TC (45%) and HDL-C (12%). NEA, NG and DEG alone decreased TC maximally by 58% and HDL-C maximally by 67%, CMA and P were without influence.

Pharmacological activities of the progestin STS 557.

This paper reports on pharmacological properties of 17 alpha-cyano-methyl-17 beta-hydroxy-estra-4, 9-dien-3-one (STS 557), which were obtained from basic screening investigations. At high doses (100 mg/kg i.p.