Publications by authors named "R Thayan"

Article Synopsis
  • - This study focused on how the dengue virus affects host cell mechanisms and gene expression, highlighting its potential for early prediction and detection of the disease in patients.
  • - Using RNA sequencing, researchers compared the transcriptomes of 16 dengue patients to 10 healthy individuals, identifying thousands of differentially expressed genes (DEGs) associated with various dengue severities.
  • - Key findings included consistent upregulation of certain genes across all dengue patients, providing potential biomarkers for predicting severe dengue, and the involvement of critical biological pathways related to immune response and viral processes.
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Asia remains vulnerable to new and emerging infectious diseases. Understanding how to improve next generation sequencing (NGS) use in pathogen surveillance is an urgent priority for regional health security. Here we developed a pathogen genomic surveillance assessment framework to assess capacity in low-resource settings in South and Southeast Asia.

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Background And Objectives: While influenza circulates year-round in Malaysia, research data on its incidence is scarce. Yet, this information is vital to the improvement of public health through evidence-based policies. In this cross-sectional study, we aimed to determine the trends and financial costs of influenza.

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