Publications by authors named "R Thanacoody"
Introduction: Ibogaine is a psychoactive alkaloid derived from the root bark of the West African shrub . It is not licensed in the United Kingdom but is used by individuals to alleviate drug or alcohol use.
Methods: A retrospective analysis of telephone enquiries involving ibogaine between 1 January 2012 and 31 December 2022 to the United Kingdom National Poisons Information Service was performed.
Aims: Review the effectiveness and dosing of L-carnitine for valproic-acid induced toxicity.
Methods: A literature review of the pharmacokinetics and clinical use of L-carnitine was performed.
Results: Valproic acid is a fatty acid used for numerous therapeutic indications ranging from epilepsy to bipolar disorder.
Objective: To evaluate a decade of reported paediatric opioid poisoning cases in the UK.
Methods: The National Poisons Information Service (NPIS) telephone enquiries database (UK Poisons Information Database) was searched for calls regarding opioid poisoning in children under 18 years from 2012 to 2021. The NPIS online clinical guidance database TOXBASE was searched for accesses relating to opioids for both adults and children.
Article Synopsis
- The Royal College of Emergency Medicine's Toxicology Special Interest Group partnered with the UK National Poisons Information Service and Guy’s and St Thomas’ NHS Foundation Trust to create guidance for emergency department clinicians on handling acute opioid toxicity in adults.
- The guidance includes advice on identifying cases of acute opioid toxicity and offers recommendations for treatment options and secondary prevention strategies.
- Emphasis is placed on utilizing the best available evidence to inform these recommendations and improve patient care.