The probiotic Lacticaseibacillus rhamnosus SD11 alleviates the progression of liver and colon damage through modulation of inflammation and tight junction proteins in streptozotocin-induced diabetic mice.

Lacticaseibacillus rhamnosus SD11 (SD11) has several health benefits for the host, including antidiabetic, anti-inflammatory, and antimicrobial effects. However, the antidiabetic mechanism of SD11 has not been clearly elucidated. The current study assessed the effects of SD11 and the associated underlying mechanisms on streptozotocin (STZ)-induced diabetic mice.

Aggregation and adhesion ability of various probiotic strains and species: An study.

Background/purpose: The ability of probiotics to inhibit adhesion is a crucial characteristic that prevents colonization and infection progression. This study aimed to explore aggregation, adhesion, and cell surface characterization of probiotic and strains and to evaluate the effect of probiotics and their cell-free supernatants (CFSs) as postbiotics on adhesion to human oral keratinocytes.

Materials And Methods: Eight probiotic strains and five reference strains were tested for autoaggregation, coaggregation, adhesin on human oral keratinocytes (H357), and cell surface properties.

Anticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation.

Probiotics and prebiotics have been considered as alternative approaches for promoting health. This study aimed to investigate the anticandidal potential of various probiotic Lactobacillus strains and their cell-free supernatants (CFSs). The study assessed the impact of inulin and some fruits as prebiotics on the growth of selected probiotic strains in relation to their anticandidal activity, production of short-chain fatty acids, total phenolic content, and antioxidant activity.

Unlocking the genetic potential of strains: Medical applications of a promising probiotic for human and animal health.

is a group of probiotic strains that have gained popularity for their potential health benefits such as promoting digestive health, boosting the immune system, improving lactose digestion, preventing and treating antibiotic-associated diarrhea, reducing the severity and duration of certain infections, and preventing the formation of dental plaque. In particular, strains SD4 and SD11 have promising human and animal health applications due to their ability to inhibit the growth of harmful pathogens. This study presents an genomic analysis of strains SD4 and SD11.