Publications by authors named "R Tanke"
Article Synopsis
- The study investigated the current practices and outcomes of genetic evaluations in Dutch children with dilated cardiomyopathy, focusing on genotype-phenotype correlations for prognosis.
- A total of 144 children were analyzed, with 74% undergoing genetic testing; findings showed that 36% had likely pathogenic or pathogenic variants, which were linked to poorer outcomes.
- The results suggest that genetic testing is crucial for predicting prognosis in these children, and it should be included in their clinical evaluations regardless of the initial diagnosis.
Aims: We aimed to determine whether in children with dilated cardiomyopathy repeated measurement of known risk factors for death or heart transplantation (HTx) during disease progression can identify children at the highest risk for adverse outcome.
Methods And Results: Of 137 children we included in a prospective cohort, 36 (26%) reached the study endpoint (SE: all-cause death or HTx), 15 (11%) died at a median of 0.09 years [inter-quartile range (IQR) 0.
Objectives: Our goal was to report the long-term serial follow-up after transatrial-transpulmonary repair of tetralogy of Fallot (TOF) and to describe the influence of the timing of the repair on outcome.
Methods: We included all patients with TOF who had undergone transatrial-transpulmonary repair between 1970 and 2012. Records were reviewed for patient demographics, operative details and events during the follow-up period (death, pulmonary valve replacement, cardiac reinterventions and hospitalization/intervention for arrhythmias).
A single 6-min walk test (6MWT) can be used to identify children with dilated cardiomyopathy (DCM) with a high risk of death or heart transplantation. To determine if repeated 6MWT has added value in addition to a single 6MWT in predicting death or heart transplantation in children with DCM. Prospective multicenter cohort study including ambulatory DCM patients ≥ 6 years.
View Article and Find Full Text PDFBackground: Dilated cardiomyopathy (DCM) in children is an important cause of severe heart failure and carries a poor prognosis. Adults with heart failure are at increased risk of anxiety and depression and such symptoms predict adverse clinical outcomes such as mortality. In children with DCM, studies examining these associations are scarce.
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