Tomographic scintigraphy of regional myocardial perfusion.

Estimation of the extent of regional ischemia by scintigraphic methods has been hampered by the geometric constraints of two-dimensional imaging. Myocardial perfusion scintigraphy was performed using the Fresnel zone-plate tomographic camera after the injection of Tc-99m microspheres (20-40 micron) into a coronary artery. Coronary artery occlusion was performed in six dogs by embolization via a catheter guidewire system.