Publications by authors named "R Takenaka"
Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required.
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- A study looked at the safety of continuing blood thinners (warfarin and DOACs) in patients needing a stomach procedure for early cancer.
- It found that people taking warfarin didn't have any bleeding after the procedure, while some people taking DOACs did.
- The researchers suggest that it's safer to keep using warfarin and that stopping DOACs too close to the procedure can lead to more bleeding problems.
Article Synopsis
- The () gene is identified as a maternal-effect lethal gene that regulates core histones, but existing mutant strains may have background genetic mutations affecting results.
- Researchers developed two new tools: a CRISPR/Cas9 knockout for genetic analysis and an epitope-tagged allele for studying cellular effects, confirming that the gene causes maternal-effect lethality that can be mitigated by reducing histone gene copies.
- Despite previous beliefs, they found that the gene does not repress core histone transcript levels, leaving the molecular reasons for its lethal effects still unclear.
Background: This study aimed to identify the efficacy of increasing the dose of stereotactic body radiotherapy (SBRT) for lung cancer.
Method And Materials: Patients who received SBRT for primary lung cancer between 2002 and 2021 were evaluated retrospectively. The patients were categorized into the 48, 50, and 55 Gy groups according to the prescribed dose.