Use of laser-assisted indocyanine green angiography to optimize supraclavicular flap perfusion.

Introduction: The supraclavicular flap (SCF) is pliable and suited for various reconstructions but faces drawbacks like distal flap necrosis and size constraints. This study assesses SCF perfusion using laser-assisted angiography and SPY-Q software, marking the first to describe the analysis achievable with indocyanine green (ICG) angiography in SCF reconstructions. We hypothesized that SPY-Q can enhance surgical precision and improve SCF design for head and neck reconstruction.

Clinical Impact of Neoadjuvant Therapy for Resectable Pancreatic Ductal Adenocarcinoma: A Single-Center Retrospective Study.

Background: Neoadjuvant therapy is recommended for treating resectable pancreatic ductal adenocarcinoma (PDAC); however, its appropriate use in patients with resectable PDAC remains debatable.

Objective: This study aimed to identify independent poor prognostic factors and evaluate the clinical significance of neoadjuvant therapy in patients with resectable PDAC.

Methods: We retrospectively reviewed consecutive patients diagnosed with resectable PDAC at our institute between January 2003 and December 2022.

Efficacy and Safety of Switching Between Anti-CGRP Monoclonal Antibodies: A Detailed Monthly and Long-term Follow-up Study and Literature Review.

Objective Switching from one anti-calcitonin gene-related peptide monoclonal antibody (CGRP mAb) to another can be beneficial for treating patients with migraine who do not respond well to the first CGRP mAb. However, detailed and long-term follow-up reports of both efficacy and safety remain insufficient. We conducted a case-series analysis of patients with migraine who switched from galcanezumab to erenumab, both belonging to the class of CGRP mAbs.

Development of a quantitative assessment for abnormal flexor synergy index in patients with stroke: a validity and responsiveness study.

Background: Arm-lifting movements (shoulder flexion) are essential for upper extremity rehabilitation after a stroke. Abnormal flexor synergy (elbow flexion) is frequently observed during shoulder flexion, impeding functional improvement. However, no quantitative method exists for assessing abnormal flexor synergy.