[Adherence of patients with stable angina to treatment with trimetazidine MR and frequency of emergency medical care: results of the EFFECT study].

The adherence of patients with stable angina to antianginal therapy is the key factor of controlling the disease. The purpose of the study was to evaluate the relationship of adherence of patients with stable angina to treatment with trimetazidine modified release (MR) with frequency (risk) of emergency medical care. We consistently included in the study patients with stable angina in primary health care.

[Effectiveness and safety of losartan and its combination with hydrochlorothiazide in patients with hypertension: in result study].

There are limited data on the results of Russia's use of losartan in clinical practice for the treatment of patients with arterial hypertension (AH). The purpose of the study was to assess the efficacy and safety of losartan and its fixed combination with hydrochlorothiazide (HCTZ) in patients with hypertension. Primary care physicians (n=644) for 8 weeks evaluated outcomes of treatment of hypertensive patients who were assigned to losartan monotherapy (12.

[Antianginal efficacy and tolerability of ivabradine in the therapy of patients with stable angina: results of the CONTROL study].

Control of heart rate (HR) is an important target during treatment of patients with stable angina. In a number of cases it can be achieved by the use of beta-adrenoblockers. But often a necessity arises to enhance pulse slowing therapy with the use of combinations of drugs exerting negative chronotropic effect.

[Effect of arterial hypertension on sexual health of men and their quality of life. Resuts of BOLERO study].

Analysis of results of epidemiological BOLERO study showed that 2/3 of men with uncontrolled arterial hypertension noted problems in sexual life. Severity of problems in this sphere of life of men correlated positively with age, as well as with presence of difficulties at work, increased fatigability, impossibility to be involved in favorite activity (hobby), disturbances of nocturnal sleep (as assessed by GQLI questionnaire). As a result of 8 weeks therapy which included indapamide retard number of patients noting substantial influence of sexual problems on their habitual way of life (CQLI score >3) decreased almost 2 times (from 25 to 13%, p<0,001).

[Effective treatment of arterial hypertension in women reduces frequency of calls for medical aid due to emergency indications. Data from the AFINA study].

Results of the study of efficacy of 12 weeks antihypertensive therapy of women with uncontrolled arterial hypertension (AH) in ambulatory conditions are presented. It has been shown that therapy comprising controlled release indapamide allows to achieve greater lowering of arterial pressure (AP) as well as higher frequency of its target level (55%) compared with ordinary treatment (37%, p<0.001), adjusted odds ratio (OR) 2.