Antibiotic resistance of crystalline bacterial ingrowth in a corneal graft.

Four recent reports have described the clinical appearance of fine needle-like opacities in the corneal stroma of six patients. In five of these patients these developed in a corneal graft. Histologically, all the corneal buttons had bacterial ingrowth between the stromal lamellae, with a striking lack of inflammatory response.

Improved vision following penetrating keratoplasty for pseudophakic corneal edema--visual results.

We studied prospectively 20 consecutive eyes of 17 patients who underwent penetrating keratoplasty for pseudophakic corneal edema. Copeland intraocular lens implants were retained in all cases initially, although one implant was subsequently removed. The visual results were analyzed at 12 and 24 months.

Posterior corneal pigmentation and fibrous proliferation by iris melanocytes.

Pigmentation of the posterior corneal surface results either from endothelial phagocytosis of free melanin pigment or from the presence of iris melanocytes, iris pigment epithelial cells, or pigment-containing macrophages on the posterior corneal surface. Although this is occasionally seen clinically, it is more often noted at histopathologic evaluation after operative or accidental ocular trauma. Three cases of posterior corneal pigmentation by iris melanocytes are reported.

The keratopathy of Crohn's disease.

A distinctive subepithelial keratopathy developed in four adult patients with Crohn's disease (granulomatous ileocolitis). Small, bilateral, symmetrical subepithelial, and anterior proliferative infiltrates and scarring were present 2 to 3 mm inside the entire corneoscleral limbus. Vision was not affected because the lesions spared the central cornea.