Publications by authors named "R T Munhoz"
Observational studies suggest a U-shaped association between serum potassium (K⁺) levels and mortality in patients with chronic heart failure (CHF). However, the mode of death in patients with HF and K⁺ disorders remains speculative. To investigate the association between potassium disorders and the mode of death in patients with CHF.
View Article and Find Full Text PDFBackground: There is limited information on rare spinocerebellar ataxia (SCA) variants, particularly in the Canadian population. This study aimed to describe the demographic and clinical features of uncommon SCA subtypes in Canada and compare them with international data.
Methods: We conducted a case series and literature review of adult patients with rare SCA subtypes, including SCA5, SCA7, SCA12, SCA14, SCA15, SCA28, SCA34, SCA35 and SCA36.
Article Synopsis
- * Research using cryo-electron microscopy reveals that the structure of α-synuclein filaments varies between different diseases, with a unique fold identified in atypical MSA that includes both neuronal and oligodendroglial pathology.
- * The study suggests that different disease entities can be classified based on the specific folds of α-synuclein filaments, linking distinct biochemical properties of the protein to the types of cells affected in various conditions.