GaitSmart Rehabilitation Exercise Programme for Gait and Mobility Issues: A NICE Medical Technologies Guidance.

GaitSmart (Dynamic Metrics Ltd) is a class I CE-marked sensor-based digital technology designed to measure lower limb movement via sensors placed on the body. GaitSmart aims to identify any problems with gait, and provide a personalised rehabilitation programme via the integrated vGym app. The company identified people referred for knee or hip replacement and people at risk of falling as potentially being able to benefit from GaitSmart.

Radiofrequency thermal ablation of giant placental chorioangioma complicated with fetal hydrops: a case report and successful outcome.

Objectives: Chorioangiomas are the most frequently occurring type of benign tumour of the placenta. However, large chorioangiomas greater than 4 cm are rare and can be more frequently associated with serious complications such as: polyhydramnios, hydrops fetalis, fetal anaemia, intrauterine growth restriction, preterm birth, and an increased risk of perinatal mortality. Importantly timely prenatal diagnosis with close surveillance alongside potential intrauterine intervention can prove impactful on pregnancy outcome and fetal survival.

Inter-modality source coupling: a fully automated whole-brain data-driven structure-function fingerprint shows replicable links to reading in large-scale (N~8K) analysis.

We propose a method called inter-modality source coupling (IMSC) to study the coupling between the function and structure of the brain and its relationship to reading ability in school-age children. We performed an analysis focused on the relationship of IMSC to overall reading score. Our findings indicate that key brain regions are linked to differences in function-structure coupling in the context of reading ability and language processing.

Defect dynamics in cholesterics: beyond the Peach-Koehler force.

The Peach-Koehler force between disclination lines was originally formulated in the study of crystalline solids, and has since been adopted to provide a notion of interactions between disclination lines in nematic liquid crystals. Here, we argue that the standard formulation of this interaction force seemingly fails for materials where there is a symmetry-broken ground state, and suggest that this is due to the interaction between disclination lines and merons: non-singular yet non-trivial topological solitons. We examine this in the context of chiral nematic (cholesteric) liquid crystals, which provide a natural setting for studying these interactions due to their energetic preference for meron tubes in the form of double-twist cylinders.

Correction: An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond.

[This corrects the article DOI: 10.1371/journal.pone.