Publications by authors named "R T Mavenyengwa"
Background: SARS-CoV-2 continues to be a major issue in resource-limited settings, particularly owing to the limited supply of vaccinescaused by inequitable distribution.
Objective: To monitor diagnostic gene targets to identify potential test failures caused by mutations, which is important for public health.
Methods: Here we analysed the genome sequence of SARS-CoV-2 from the second wave in Zimbabwe.
The introduction of effective vaccines in December 2020 marked a significant step forward in the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is a need to describe the current status of vaccine uptake in the continent. An exploratory study was undertaken to investigate these aspects, current challenges, and lessons learnt across Africa to provide future direction.
View Article and Find Full Text PDFBackground: Streptococcus agalacticae (Group B Streptococcus, GBS) is one of the most important causative agents of serious infections among neonates. This study was carried out to identify antibiotic resistance and virulence genes associated with GBS isolated from pregnant women.
Methods: A total of 43 GBS isolates were obtained from 420 vaginal samples collected from HIV positive and negative women who were 13-35 weeks pregnant attending Antenatal Care at Chitungwiza and Harare Central Hospitals in Zimbabwe.
Background: Cancer and sepsis comorbidity is a major public health problem in most parts of the world including Zimbabwe. The microbial aetiologies of sepsis and their antibiograms vary with time and locations. Knowledge on local microbial aetiologies of sepsis and their susceptibility patterns is critical in guiding empirical antimicrobial treatment choices.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the vaginal microbiota and immune factors in pregnant African women, comparing those who are HIV-infected to those who are HIV-uninfected, highlighting significant differences in microbiota diversity and structure between the two groups.
- Results indicate that HIV infection is linked to a more diverse vaginal microbiota and an increased risk of preterm birth, with HIV-infected women experiencing a 31% risk of preterm birth compared to 15.3% for HIV-uninfected women.
- The researchers suggest that more longitudinal studies with precise gestational age tracking are necessary to further explore these findings and their implications for maternal and neonatal health.