Publications by authors named "R T M Caldas"
When developing general-purpose robot software components, we often lack complete knowledge of the specific contexts in which they will be executed. This limits our ability to make predictions, including our ability to detect program bugs statically. Since running a robot is an expensive task, finding errors at runtime can prolong the debugging loop or even cause safety hazards.
View Article and Find Full Text PDFObjective: to analyze the spatial-temporal pattern of childbirths and flow of postpartum women assisted at a regional reference maternity hospital.
Methods: ecological study of 4,081 childbirths, between September 2018 and December 2021, at a public maternity hospital in the Baixo Tocantins region, Pará, Brazil. With data collected from five sources, a geographic database was constructed, and spatial analysis was used with Kernel density interpolator.
Genome-wide association study analysis of single nucleotide variants in associated with IL-6 inflammatory response in visceral leishmaniasis.
Parasitology
December 2024
Elevated levels of IL-6 in plasma are associated with the severity of visceral leishmaniasis (VL). The clinical manifestations of VL vary among patients, influenced by host factors and the virulence of the parasite. Considering that severe VL may result from an exaggerated inflammatory response, this study investigated whether IL-6 could serve as a biomarker to identify pro-inflammatory virulence factors.
View Article and Find Full Text PDFArticle Synopsis
- The increasing number of patients with temporomandibular disorders (TMD) and the diagnostic challenges faced by general dentists highlight the need for artificial intelligence in improving TMD diagnosis.
- This study assessed a machine-learning model that classifies TMDs using patient data aligned with the International Classification of Orofacial Pain.
- Results showed the model could accurately classify joint pain at 84% and myofascial pain at 78%, indicating that decision tree-based machine learning can significantly aid in diagnosing TMD.
Nintedanib, a tyrosine kinase inhibitor, is a cornerstone in the management of idiopathic pulmonary fibrosis through its anti-fibrotic effects; however, its impact on wound healing is less studied. We present a case of medication-related osteonecrosis of the jaw (MRONJ) following the initiation of nintedanib. The patient's presentation prompted a drug holiday of nintedanib, resulting in a marked improvement in her symptoms.
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