Diagnostic Test Precision of Modified Carbapenem Inactivation Method and Carbapenemase Nordmann-Poirel Test for Phenotypic Detection of Carbapenemase Production in Enterobacterales: A Systematic Review.

Carbapenem-resistant Enterobacterales, particularly those that produce carbapenemases, pose a significant public health concern due to very limited treatment options. The timely identification of carbapenemase-producing Enterobacterales (CPE) is essential for putting in place efficient infection control measures and selecting appropriate antimicrobial therapies, thereby improving the clinical outcome of the patient. The purpose of this systematic review is to compare the diagnostic accuracy and practicality between two phenotypic tests, namely the modified carbapenem inactivation method (mCIM) and carbapenemase Nordmann-Poirel (Carba NP) test, in detecting carbapenemase production by Enterobacterales and thereby aiding the clinician in making a decision to choose an appropriate test for their phenotypic detection.

Molecularly imprinted nanoparticles doped graphene oxide based electrochemical platform for highly sensitive and selective detection of L-tyrosine.

A highly sensitive and selective electrochemical sensor was developed using a surface modified glassy carbon electrode (GCE) through molecularly imprinted polymerization on the surface of vinyltrimethoxysilane (VTMS) coated magnetic nanoparticle (FeO) decorated silver nanoparticles incorporated graphene oxide, GO (VTMS-FeO/AgGO) for L- Tyrosine (Tyr) detection. A molecular imprinting technique based on free radical polymerization was applied to synthesize molecularly imprinted Methacrylic acid (MAA) and Acrylamide (AA) grafted VTMS-FeO/AgGO polymer (MAA/AA-g- VTMS-FeO/AgGO) designated as MIP and non-imprinted polymer (NIP). The structure and morphology of the prepared polymers were FTIR, XRD, FE-SEM and VSM.

Seroprevalence and risk factors for influenza A viruses in pigs in Peninsular Malaysia.

Following a series of H5N1 cases in chickens and birds in a few states in Malaysia, there was much interest in the influenza A viruses subtypes that circulate among the local pig populations. Pigs may act as a mixing vessel for avian and mammal influenza viruses, resulting in new reassorted viruses. This study investigated the presence of antibodies against influenza H1N1 and H3N2 viruses in pigs from Peninsular Malaysia using Herdcheck Swine Influenza H1N1 and H3N2 Antibody Test Kits.