Control of tumour development and growth by the immune system critically defines patient fate and survival. What regulates the escape of colorectal tumours from destruction by the immune system remains currently unclear. Here, we investigated the role of intestinal synthesis of glucocorticoids in the tumour development during an inflammation-induced mouse model of colorectal cancer.
View Article and Find Full Text PDFUsage-based theories of language acquisition are thought to rely on domain-general learning mechanisms, such as mastering familiar routines by rote before generalizing to novel unfamiliar instances. If so, then the role of familiarity should extend to non-linguistic domains, like music. The purpose of the present study was to test the role of familiarity in children's learning of affective meaning of music.
View Article and Find Full Text PDFPurpose: To evaluate terpinen-4-ol lid scrubs (Cliradex) with Microblepharoexfoliation (MBE) (BlephEx) in the treatment of Demodex blepharitis.
Methods: An Institutional Review Board (IRB) approved the randomized prospective double-masked trial of 50 patients with Demodex positive blepharitis. All subjects were given an in-office MBE treatment and randomized to masked lid scrubs (terpinen-4-ol or sham) twice daily for 1 month.