Publications by authors named "R Stephen Amato"

The present research aimed to evaluate the effects of the continuative dietary administration of a hemp oil extract containing cannabinoids (cannabidiol, CBD) on the macroscopic morphology, morphometry, and enzymatic activity of different intestinal tracts as well as on the production of short chain fatty acids (SCFA) in the cecum of growing rabbits. The research was performed on 16 rabbits randomly selected from 2 experimental groups (8 per group). In detail, 42, sixty-day-old New Zealand White x California rabbits (sex ratio 1:1, average weight 1621.

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Hereditary breast cancer accounts for 5-10% of all cases, with pathogenic variants in and other susceptibility genes playing a crucial role. This study elucidates the prevalence and spectrum of germline variants in 13 cancer predisposition genes among high-risk hereditary breast cancer patients from Southern Italy. We employed next-generation sequencing (NGS) to analyze 254 individuals selected through genetic counseling.

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Article Synopsis
  • * The disease presents symptoms like anemia and splenomegaly, with treatment options including JAK inhibitors (like Ruxolitinib) and other supportive therapies, while allogeneic stem cell transplantation is the only potential cure for eligible patients.
  • * Advances in Spatially Resolved Transcriptomics (SRT) allow for detailed analysis of gene expression in tissues, enhancing our understanding of the tumor microenvironment and cellular interactions in MF.
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Introduction: At San Martino IRCCS Hospital in Genoa, Italy, emergency and urgent surgery is classified according to the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) classification, whereby cases are divided into two categories and colour-coded accordingly: - EMERGENCY - (Colour-code: RED) "Surgery to be performed within minutes"; - URGENCY - (colour-code: YELLOW) "Surgery to be performed within hours". In this context, it is essential that the emergency surgical team gets clear and complete information from the proposing surgeon, in order to complete the surgical list.

Methods: Between 14 April 2023 and 23 July 2023, a new method of requesting urgent and emergency surgery by filling out an online form was tested.

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Introduction: Nosocomial structures pose a high risk of . contamination due to complex water systems with challenging disinfection; moreover, the risk of severe legionellosis as a consequence of nosocomial exposure is very high in settings characterized by vulnerable patient conditions.

Methods: In the present work, we described the results of 7 years of environmental surveillance in a reference hospital in Liguria, in which a specific water safety plan (WSP) has been implemented in 2017, including data collected during the COVID-19 pandemic.

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