Publications by authors named "R Steinkamp"
CORUM (https://mips.helmholtz-muenchen.de/corum/) is a public database that offers comprehensive information about mammalian protein complexes, including their subunits, functions and associations with human diseases.
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- The study focuses on the advancements in reconstructing microbial genomes from metagenomic data and highlights the variability in data quality that needs assessment.
- The authors introduced a new tool called CoCoPyE, which utilizes a two-stage process to accurately predict genome quality by identifying genomic markers and refining estimates with machine learning.
- CoCoPyE outperformed existing tools in accuracy during simulations and provides both a web server and Python implementation for easy integration into genome analysis workflows.
Plant terrestrialization brought forth the land plants (embryophytes). Embryophytes account for most of the biomass on land and evolved from streptophyte algae in a singular event. Recent advances have unravelled the first full genomes of the closest algal relatives of land plants; among the first such species was Mesotaenium endlicherianum.
View Article and Find Full Text PDFThe CORUM database has been providing comprehensive reference information about experimentally characterized, mammalian protein complexes and their associated biological and biomedical properties since 2007. Given that most catalytic and regulatory functions of the cell are carried out by protein complexes, their composition and characterization is of greatest importance in basic and disease biology. The new CORUM 4.
View Article and Find Full Text PDFThe function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the characterization of relationships between genes and phenotypes. The EUMODIC consortium developed and validated robust methodologies for the broad-based phenotyping of knockouts through a pipeline comprising 20 disease-oriented platforms.
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