Publications by authors named "R Starzynski"
With the current state of knowledge regarding disorders of facial bone development, including anodontia, the development of a suitable animal model for preclinical studies is essential. The agenesis of dental buds occurs in about 25% of the human population. Prospects for treatment include the use of growth factors, stem cells, and bioengineering.
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- Dietary lipids are crucial for energy, cell structure, and various physiological processes, with PUFAs being examined in diets for pigs in this study.
- The research focused on two pig breeds, Polish Landrace and PLxDuroc, comparing a normal diet to a PUFAs-enriched one while analyzing liver miRNA profiles for their impact on important agricultural traits.
- Findings highlighted significant gene interactions related to traits like meat color and fat thickness, revealing specific miRNA clusters linked to muscle development and other essential biological functions.
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- Preterm infants are highly susceptible to iron deficiency, but understanding of their iron regulation is limited.
- The research aimed to create a suitable animal model by inducing prematurity in piglets, allowing assessment of iron status similar to that of preterm human infants.
- Findings showed that preterm piglets had lower body weight and plasma iron but higher tissue iron and levels of iron-regulatory hormones, indicating a unique pattern of iron metabolism that suggests functional iron deficiency and accumulation.
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- Some health disorders, like obesity and type 2 diabetes, are linked to poor diets, impacting liver health based on diet type and duration.
- The study examined the effects of various high-fat diets on mouse liver protein profiles using complex techniques like two-dimensional electrophoresis and mass spectrometry.
- Results showed 32 different protein spots based on diet variations, with high polyunsaturated fatty acids affecting proteins related to metabolism and oxidative stress.
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- * The study investigated iron transfer efficiency across the placenta as a potential reason for the observed differences in iron status between wild boar and Polish Large White (PLW) piglets.
- * Analysis revealed no major differences in iron transporter gene expression between the two species, but wild boar placentas showed higher levels of certain enzymes that aid in iron export to the fetus.