Publications by authors named "R Stanton"
This report represents the conclusions of 15 experts in nephrology and endocrinology, based on their knowledge of key studies and evidence in the field, on the role of continuous glucose monitors (CGMs) in patients with diabetes and chronic kidney disease (CKD), including those receiving dialysis. The experts discussed issues related to CGM accuracy, indications, education, clinical outcomes, quality of life, research gaps, and barriers to dissemination. Three main goals of management for patients with CKD and diabetes were identified: (1) greater use of CGMs for better glycemic monitoring and management, (2) further research evaluating the accuracy, feasibility, outcomes, and potential value of CGMs in patients with end-stage kidney disease (ESKD) on hemodialysis, and (3) equitable access to CGM technology for patients with CKD.
View Article and Find Full Text PDFIntroduction: The increasing prevalence of shiftwork among young adults poses significant health risks, primarily due to its disruptive effects on sleep, nutrition and physical activity. Addressing these risks necessitates the development of tailored, evidence-based resources to support these key health behaviours. Participatory research approaches, engaging those with relevant lived experience (i.
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- Cyclin-dependent kinase 8 (CDK8) helps control how viruses, especially the human cytomegalovirus (HCMV), grow in our cells by affecting important processes in their life cycles.
- Scientists tested some drugs that stop CDK8 to see if they could help fight HCMV, and they found that these drugs made the virus grow much less in cell cultures.
- The research showed that CDK8 is crucial for HCMV's later stages of growth, and using CDK8 inhibitors together with other treatments could work really well against the virus.
Article Synopsis
- CMV (Cytomegalovirus) is a genus of herpesviruses that has evolved alongside primates and typically causes lifelong infections, being mostly harmless in healthy individuals but dangerous for those with weakened immune systems.
- The human CMV genome is highly complex, containing at least 15 gene families, with the RL11 gene family being the largest and vital for immune evasion, yet showing high variability, making evolutionary relationships hard to trace.
- This study used genomic and phylogenetic analysis to trace the evolution of the RL11 gene family, revealing that it is unique to certain primates and resulted from early gene duplications followed by specific gene losses in different lineages.
Article Synopsis
- Adequate prenatal care is crucial for the health of mothers and children, but its utilization is lower in rural areas, particularly highlighted during the COVID-19 pandemic when telehealth became more prevalent.
- A study analyzing PRAMS data found that, in 2020, there was a 12% decrease in adequate prenatal visits compared to previous years, with rural respondents facing higher barriers to care access.
- After adjusting for these barriers, the urban-rural differences in prenatal care adequacy during the pandemic were less significant, indicating that addressing these barriers could improve access to care.