To vaccinate or not to vaccinate - BNT162b2 seroconversion rate and side effects among Polish healthcare workers.

Objectives: The study aimed to analyze the effect of BNT162b2 vaccination among Polish healthcare workers in terms of serologic response and adverse events.

Material And Methods: A questionnaire survey covered data in the period January 1-March 31, 2021 gathered in 2 hospitals in Wielkopolska, Poland. Additionally, serological analysis (SARS-CoV-2 anti-S protein IgG) was performed.

Tissue expression of interleukin 2 (IL-2) and IL-2 receptor (IL-2R(alpha)/CD25) in non-Hodgkin B-cell lymphomas in children: correlations with clinical data.

The study aimed at analysis of tissue expression of interleukin 2 (IL-2) and subunit alpha of its receptor (IL-22R(alpha)/CD25) in B-cell non-Hodgkin lymphomas (B-cell NHLs) in children as related to selected clinical data. The studies were performed on an archival tissue material originating from children with B-cell NHLs (n=26) using avidin-biotin-peroxidase complex method and in-situ hybridization with biotinylated tyramine amplification signal (ImmunoMax technique). As compared with non-neoplastic lesions, in B-cell NHLs a significantly higher expression was noted of both IL-2 and IL-22R(alpha).

Epstein-Barr virus (EBV) infection in B-cell non-Hodgkin's lymphomas in children: virus latency and its correlation with CD21 and CD23 molecules.

Epstein Barr virus (EBV) infection of human B lymphocytes in vitro results in immortalisation of the cells and augmented membranous expression of numerous B-cell activation molecules, including CD23. Other studies demonstrated that only those B lymphocytes which carry the surface CD21 (EBV receptor) become transformation-competent. Inspired by the relatively unclear relations between expression of EBV and those of CD21 and CD23 in in vivo conditions we have decided to define correlations between tissue markers of EBV and of CD21 and CD23 molecules in B-cell non-Hodgkin's lymphomas (NHLs) in children.

Tissue markers of Epstein-Bar virus (EBV) infection in B-cell non-Hodgkin's lymphomas.

Unlabelled: AIM OF the study was to analyze the cellular expression of two latent Epstein-Barr virus (EBV) proteins and one of the lytic protein, two small RNAs (EBERs) and EBV DNA in children and adult patients with B-cell non-Hodgkin's lymphomas (NHLs) and to characterise more strictly patterns of EBV latency in both groups of patients in our country.

Material And Methods: The studies were performed on an archive tissue material from 26 children and from 27 adults with B-cell NHLs. The studies used immunocytochemical techniques, in situ hybridisation, and PCR.

Morphological and molecular diagnosis of a fatal form of EBV infectious mononucleosis in a child.

Mortal cases of acute Epstein-Barr virus (EBV) infection in the form of mononucleosis have been seldom described and used to be related to complications of the disease. In this report, the case of a 3-year-old girl is described, with severe form of infectious mononucleosis, deceased in the course of respiratory-circulatory insufficiency with a sudden cessation of heart action. Particular attention was given to histological lesions, phenotype of inflammatory cells and to expression of proteins and EBV RNAs (EBERs) in tissues, examined using immunocytochemical techniques and in situ hybridization.