Publications by authors named "R Smolarczyk"

: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. It is associated with an increased risk of somatic and mental health problems. The prevalence of binge eating disorder (BED) in women with PCOS is higher than in the healthy population.

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Introduction: Currently, progesterone is notably absent from conventional feminizing hormone therapies for transgender women. Anecdotal reports indicate the potential for health advantages following the incorporation of progesterone into treatment regimens. The primarily female hormone, progesterone naturally surges in women during the menstrual luteal phase.

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Objective: Over the decade, variety and effectiveness of contraception methods have greatly improved, resulting in increased popularity of oral contraceptive pills (OCPs). However, hormonal contraception carries the risk of multiple side effects. The lack of sufficient knowledge often leads to the development of health concerns, which can affect patient's adherence.

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Hypoxia is one of the defining characteristics of the tumor microenvironment (TME) in solid cancers. It has a major impact on the growth and spread of malignant cells as well as their resistance to common treatments like radiation and chemotherapy. Here, we explore the complex functions of hypoxia in the TME and investigate its effects on angiogenesis, immunological evasion, and cancer cell metabolism.

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Article Synopsis
  • Obesity is a major global health issue, characterized by excessive body fat that functions like an organ, disrupting metabolic processes and overall body function.
  • One key factor in obesity is low-grade inflammation, driven by pro-inflammatory substances released from fat tissue, which negatively affects insulin sensitivity and reproductive hormones.
  • The review highlights the complicated interactions between fat-derived hormones and immune responses, emphasizing the need for further research to develop targeted treatments for reproductive issues linked to obesity.
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