Publications by authors named "R Siracusa"
Background/objectives: Obesity is a major public health concern, significantly elevating the risk of developing comorbid conditions such as type 2 diabetes mellitus and cardio-vascular diseases, while also shortening life expectancy. Currently, metabolic and bariatric surgery (MBS) is one of the most effective long-term interventions for achieving substantial weight loss, alongside notable improvements in overall quality of life. However, evidence suggests that these procedures may negatively affect bone health, leading to an increased risk of fractures.
View Article and Find Full Text PDFThe journal retracts the article "Environmental risk assessment of mixture of COVID-19 treating pharmaceutical drugs in zebrafish early life stage ()" [...
View Article and Find Full Text PDFThe journal retracts the article entitled "Combined Toxicity of Xenobiotics Bisphenol A and Heavy Metals on Zebrafish Embryos ()" [...
View Article and Find Full Text PDFArticle Synopsis
- - Metabolic syndrome (MetS) is a growing public health issue linked to changes in eye health, particularly leading to conditions like diabetic retinopathy, influenced by factors such as osteopontin (OPN).
- - In a study that induced MetS in animals through a 30% fructose diet over three months, researchers tracked changes in weight, food intake, and biochemical parameters, revealing significant weight gain and alterations akin to MetS in humans.
- - Findings showed a time-dependent increase in OPN and microglia levels, alongside a decline in proteins important for cell junctions, suggesting that monitoring OPN could serve as an early indicator of retinal damage in MetS patients, potentially aiding in the prevention of serious complications