Diabetes and Hypertension at Midlife Predict Increases in Biomarkers of Dementia Among Black Americans.

Background: Compared to other racial/ethnic groups, Black Americans show accelerated brain aging beginning in midlife and exhibit higher rates and earlier onset of dementia. While these patterns are often viewed as evidence that Black Americans are more vulnerable to Alzheimer's disease, another possibility is that their high risk for chronic vascular pathologies such as high blood pressure and diabetes compromises their brain health. This hypothesis was tested in the present study.

Coronectomy of mandibular third molars with dental pathology: a prospective cohort study of 121 molars.

Purpose: Coronectomy is a valuable treatment proven safe for non-pathological mandibular third molars with an increased risk of inferior alveolar nerve injury. Coronectomy may also be useful for mandibular third molars with dentigerous cysts and caries, but this is not commonly performed due to the lack of well-designed, evidence-based studies. Here, we aim to investigate the safety of coronectomy for mandibular third molars with caries and dentigerous cysts.

Indirect Effects of Childhood Maltreatment on Posttraumatic Stress Disorder Symptoms via Emotion Regulation Difficulties.

This study tested structural equation models of associations between childhood maltreatment (CM), posttraumatic stress disorder (PTSD) symptoms, and emotion regulation (ER) difficulties in a sample of young adult college students ( = 606). The primary final model demonstrated that lack of emotional clarity and limited access to ER strategies partially mediated the association between CM and PTSD symptoms. Exploratory analyses showed that CM was also indirectly associated with PTSD symptoms via lack of emotional awareness, nonacceptance, and difficulty controlling impulses.

Impact of Removing the Monitoring Requirements for Holdings with Atypical Scrapie in Great Britain.

Atypical scrapie (AS) is a transmissible spongiform encephalopathy (TSE) that affects sheep and goats. Low within-flock incidence suggests that AS is not transmissible between animals, and testing of all animals that exit positive flocks for two years following detection (i.e.

Response Rates, Reliability, and Convergent Validity in Experience Sampling Data.

This study examined associations of compliance rate with the reliability and convergent validity of intoxication and negative affect assessments in experience sampling method (ESM) data in three samples (Veterans, Sexual Minority Men, and College Students). Convergent validity was operationalized as within-person associations between daily aggregates of random in situ assessments and retrospective daily assessments or transdermal alcohol assessments. Measures with lower ICC require more assessments for a reliable aggregate (e.