Publications by authors named "R Simonini"

Article Synopsis
  • Carnivorous polychaetes, like Halla parthenopeia, have unique physical and behavioral traits that aid in hunting and self-defense, particularly in the Mediterranean Sea where they prey on clams.
  • The study explores H. parthenopeia's anatomy, highlighting the role of its specialized mucus glands in immobilizing prey and possibly releasing bioactive compounds crucial for its survival and adaptation.
  • Key findings indicate that the worm's anatomical defenses, such as a thick cuticle and the secretion of toxic substances like Hallachrome, enhance its ability to protect itself from predators and pathogens while effectively hunting bivalves.
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Antimicrobial resistance is a critical global health issue, with rising resistance among bacteria and fungi. Marine organisms have emerged as promising, but underexplored, sources of new antimicrobial agents. Among them, marine polychaetes, such as , which possess chemical defenses, could attract significant research interest.

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We aimed to demonstrate the applicability of Snyder's arthroscopic classification of rotator cuff tears (RCT) in shoulder ultrasound (US) and to compare it with MR arthrography (MRA). Forty-six patients (34 males; mean age:34 ± 14 years) underwent shoulder US and MRA. Two radiologists (R1 = 25 years of experience; R2 = 2 years of experience) assigned A1-4, B1-4, or C1-4 values depending on the extent of RCT in both US and MRA.

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PI-RADS 3 prostate lesions clinical management is still debated, with high variability among different centers. Identifying clinically significant tumors among PI-RADS 3 is crucial. Radiomics applied to multiparametric MR (mpMR) seems promising.

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Increasing evidence in the field of bioprospection fosters the necessity of studying poorly investigated poisonous marine invertebrates to expand knowledge on animal venom biology. Among marine annelids, amphinomid fireworms are notorious for their bearded trunk equipped with a powerful stinging capacity. Here, a methodological workflow based on analytical chemistry techniques (compound isolation followed by mass spectrometry and spectroscopy analyses) was applied to gain new insights, leading to the identification and structural elucidation of an array of natural products from Mediterranean specimens of .

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