Publications by authors named "R Simanjuntak"
The present study aimed to assess the bioequivalence of a new apixaban generic with reference formulation. Twenty-six healthy volunteers were recruited for an open-label, balanced, randomized, 2-treatment, 2-sequence, 2-period, single oral dose study. Following overnight fasting, each volunteer received 5 mg of apixaban test and reference formulations as single doses, separated by a 1-week washout period.
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- * It analyzed data from 480 hospitalized CAP patients between January 2019 and June 2020, determining antibiotic failure based on criteria like patient mortality, ICU transfer, and length of hospital stay.
- * The results showed that the DRIP score had low accuracy in predicting antibiotic failure, with a p-value indicating poor calibration and a ROC curve AUC that suggests limited effectiveness for clinical use.
Osteoarthritis (OA) contributes to significant medical and socioeconomic burden in many populations. Its prevalence is expected to rise continuously owing to the combined effects of aging and increase in risk factors, including obesity, physical inactivity, and joint injuries. Pain is a hallmark presentation of OA.
View Article and Find Full Text PDFIrregular labelling on graph is a function from component of graph to non-negative natural number such that the weight of all vertices, or edges are distinct. The component of graph is a set of vertices, a set of edges, or a set of both. In this paper we study two types of irregular labelling on dodecahedral modified generalization graph.
View Article and Find Full Text PDFBackground: Bovine pericardium collagen membrane (BPCM) had been widely used in guided bone regeneration (GBR) whose manufacturing process usually required chemical cross-linking to prolong its biodegradation. However, cross-linking of collagen fibrils was associated with poorer tissue integration and delayed vascular invasion.
Objective: This study evaluated the potential of bovine cortical bone collagen membrane for GBR by evaluating its antigenicity potential, cytotoxicity, immune and tissue response, and biodegradation behaviors.