Endovascular treatment of complex cerebral aneurysms with onyx hd-500® in 38 patients.

Objective: To report our experience with Onyx HD-500(®) (Micro Therapeutics, Inc., Irvine, CA, USA) in the endovascular treatment of complex intracranial aneurysms as an alternative to treatment with platinum coils.

Patients And Methods: Between October 2003 and December 2007, 38 patients (20 female and 18 male) were selected for inclusion in the study based on aneurysm size and dome-to-neck ratio.

Bilirubin-adsorption in 23 critically ill patients with liver failure.

Purpose: Previous studies suggest that high levels of bilirubin exert cytotoxic, neurotoxic and encephalopathic effects that themselves may lead to further deterioration of liver function and multiorgan failure. Although extracorporeal BA is not a causal therapy, there are case reports of clinical benefits of BA. The present retrospective study investigated the clinical utility and effectiveness of BA in 23 patients with liver failure.

[The inhibitory effect of puromycin and 2-thiouracil on the phytochrome-mediated synthesis of anthocyanin].

The phytochrome-mediated anthocyanin synthesis of the mustard seelding, Sinapis alba L., can be stopped by the application of relatively low concentrations of puromycin and 2-thiouracil. While actinomycin D, which has been investigated in a previous paper (LANGE and MOHR, 1965), will block phytochrome-induced anthocyanin synthesis only if it is applied before or at the onset of light, puromycin and 2-thiouracil will stop anthocyanin synthesis even if they are applied at a later stage, e.