A review of the physiological effects of microgravity and innovative formulation for space travelers.

During the space travel mission, astronauts' physiological and psychological behavior will alter, and they will start consuming terrestrial drug products. However, factors such as microgravity, radiation exposure, temperature, humidity, strong vibrations, space debris, and other issues encountered, the drug product undergo instability This instability combined with physiological changes will affect the shelf life and diminish the pharmacokinetic and pharmacodynamic profile of the drug product. Consequently, the physicochemical changes will produce a toxic degradation product and a lesser potency dosage form which may result in reduced or no therapeutic action, so the astronaut consumes an additional dose to remain healthy.

Naturally weathered polypropylene microplastic from environment and its toxic behaviour in Artemia salina.

The increasing use of polypropylene (PP) in consumer products leads to the microplastic (PP MPs) contamination of the aquatic ecosystems. Comprehensive toxicological studies of weathered/aged and new PP MPs with Artemia salina are a need of the hour. Our study explores the toxicological differences between naturally weathered (aged) and prepared new PP MPs on Artemia salina.

Mixture toxicity of TiO NPs and tetracycline at two trophic levels in the marine ecosystem: Chlorella sp. and Artemia salina.

Increasing usage of both nanomaterials and pharmaceuticals and their unabated release to the marine ecosystem pose a serious concern nowadays. The toxicity of the mixture of TiO NPs and tetracycline (TC) in the marine species are not very well covered in prior literature. The current study explores the joint toxic effects of TiO NPs and TC in a simulated marine food chain: Chlorella sp.

Enhanced Photo-Catalytic and Antibacterial Properties of Ni-Doped CdZnS Nanostructures.

The present work describe the synthesis of CdZnS and CdZnNiS nanostructures by chemical co-precipitation method. The XRD profile proved the cubic crystal structure of the samples without any impurity related phases. The reduced size from 63 to 51 Å and the dissimilarities in lattice parameters and micro-strain has been discussed by Ni addition in CdZnNiS structure.

Toxicity evaluation of nano-TiO in the presence of functionalized microplastics at two trophic levels: Algae and crustaceans.

The rising use of contaminants such as nanoparticles and microplastics has taken a heavy toll on the marine environment. However, their combined toxic effects on the species across various trophic levels remain quite unexplored. The aim of this study was to explore the effects of three surface-functionalized (carboxylated, plain, and aminated) polystyrene microplastics on nano-TiO toxicity across two trophic levels containing Chlorella sp.