Spindle Cell Squamous Cell Carcinoma of Head and Neck Region: a Clinicopathological and Immunohistochemical Study.

Spindle cell squamous cell carcinoma (SCSCC) represents a rare, dedifferentiated form of conventional squamous cell carcinoma (SCC) with propensity for head and neck. Morphological heterogeneity of this tumor poses significant diagnostic challenge for pathologists. This study aimed to evaluate detailed morphological and immunohistochemical (IHC) characteristics of a series of SCSCC cases.

Investigation of the Photoluminescence and Nonlinear Optical Properties of Ce₂O₃-TiO₂ Nanocomposites.

This paper reports the photoluminescence and nonlinear optical (NLO) properties of Ce₂O₃-TiO₂ nanocomposites synthesized via sol-gel process with different concentrations of cerium. The physical characterization studies by means of XRD indicated for the successful incorporation of Ce into the lattice of TiO₂, while the UV-visible spectra for an absorption edge shift of TiO₂ to the higher wavelength side following the Ce addition, and FESEM analysis for the morphology and particles sizes of the synthesized materials. On testing of the photoluminescence properties recorded through time-resolved fluorescence (TCSPC) technique, a decrease in the intensity of TiO₂ with that of increased Ce concentration was observed and is due to an escalation in the number of oxygen vacancies.

High-risk histomorphological features in retinoblastoma and their association with p53 expression: An Indian experience.

Introduction: Histopathological features in retinoblastoma are considered high-risk factors (HRF) for tumor progression and metastasis, thus their presence becomes an indication for adjuvant chemotherapy. Present study was undertaken to evaluate the incidence of HRF in retinoblastoma and to correlate them with p53 expression. Materials and Methods: This was a retrospective study where 17 diagnosed cases of retinoblastoma were included.

Melatonin ameliorates oxidative stress and induces cellular proliferation of lymphoid tissues of a tropical rodent, Funambulus pennanti, during reproductively active phase.

Effect of melatonin treatment on free radical production was assessed with simultaneous investigation of hormonal level (melatonin and testosterone), blastogenic response, stimulation index, and histological observation of lymphoid organs (spleen, thymus, and bone marrow) in male Indian palm squirrel (Funambulus pennanti) during reproductively active phase (RAP). Low endogenous melatonin and high testosterone level were noted during RAP. Daily subcutaneous injection of melatonin (25 μg/100 g B wt.