From Crop Residue to Corrugated Core Sandwich Panels as a Building Material.

This study explores the potential of using underutilized materials from agricultural and forestry systems, such as rice husk, wheat straw, and wood strands, in developing corrugated core sandwich panels as a structural building material. By leveraging the unique properties of these biobased materials within a corrugated geometry, the research presents a novel approach to enhancing the structural performance of such underutilized biobased materials. These biobased materials were used in different lengths to consider the manufacturing feasibility of corrugated panels and the effect of fiber length on their structural performance.

Risk of new disease activity in patients with multiple sclerosis who continue or discontinue disease-modifying therapies (DISCOMS): a multicentre, randomised, single-blind, phase 4, non-inferiority trial.

Background: Multiple sclerosis typically has onset in young adults and new disease activity diminishes with age. Most clinical trials of disease-modifying therapies for multiple sclerosis have not enrolled individuals older than 55 years. Observational studies suggest that risk of return of disease activity after discontinuation of a disease-modifying therapies is greatest in younger patients with recent relapses or MRI activity.

Tolerability and Safety of Switching from Rituximab to Ocrelizumab: Evaluating Factors Associated with Infusion Related Reactions.

Background: Ocrelizumab and rituximab are frequently used treatments for multiple sclerosis (MS). Data on switching from rituximab to ocrelizumab is limited.

Objectives: To assess the frequency, severity, and factors of infusion related reactions (IRRs) in patients with MS who switch from rituximab to ocrelizumab, compared to those who stay on rituximab.

Correlation Analysis of Ultrasonic Stress Wave Characteristics and the Destructive Strength Measurements in Cylindrical Wooden Structure.

The utility sector has been employing ultrasonic-based nondestructive evaluation (NDE) to determine the cross-sectional groundline integrity of wooden utility poles. While it is far less invasive than other methods, its efficacy has not been thoroughly studied. This study aims to fill this technical gap by analyzing the correlation between the propagational characteristics of the ultrasonic stress wave using a novel embedded waveguide technique and the existing destructive testing methods.

Brain atrophy rates in patients with multiple sclerosis on long term natalizumab resembles healthy controls.

Background: Clinically stable multiple sclerosis (MS) patients often have negligible inflammatory MRI changes. Brain atrophy may provide insight into subclinical disease progression. The objective was to compare brain atrophy rates in stable patients on long term natalizumab treatment vs.