Demystifying Large Language Models for Medicine: A Primer.

Large language models (LLMs) represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses across diverse contexts and adapting to novel tasks following human instructions. Their potential application spans a broad range of medical tasks, such as clinical documentation, matching patients to clinical trials, and answering medical questions. In this primer paper, we propose an actionable guideline to help healthcare professionals more efficiently utilize LLMs in their work, along with a set of best practices.

CT-Based Body Composition Measures and Systemic Disease: A Population-Level Analysis Using Artificial Intelligence Tools in Over 100,000 Patients.

CT-based abdominal body composition measures have shown associations with important health outcomes. Artificial intelligence (AI) advances now allow deployment of tools that measure body composition in large patient populations. To assess associations of age, sex, and common systemic diseases on CT-based body composition measurements derived using a panel of fully automated AI tools in a population-level adult patient sample.

Utilizing domain knowledge to improve the classification of intravenous contrast phase of CT scans.

Multiple intravenous contrast phases of CT scans are commonly used in clinical practice to facilitate disease diagnosis. However, contrast phase information is commonly missing or incorrect due to discrepancies in CT series descriptions and imaging practices. This work aims to develop a classification algorithm to automatically determine the contrast phase of a CT scan.

Leveraging Professional Radiologists' Expertise to Enhance LLMs' Evaluation for AI-generated Radiology Reports.

In radiology, Artificial Intelligence (AI) has significantly advanced report generation, but automatic evaluation of these AI-produced reports remains challenging. Current metrics, such as Conventional Natural Language Generation (NLG) and Clinical Efficacy (CE), often fall short in capturing the semantic intricacies of clinical contexts or overemphasize clinical details, undermining report clarity. To overcome these issues, our proposed method synergizes the expertise of professional radiologists with Large Language Models (LLMs), like GPT-3.