Publications by authors named "R Scott Nolen"
Article Synopsis
- PFOS is a common pollutant that poses various toxic risks to marine life, especially in urban and industrial coastal areas.
- This study examined the relationship between PFOS exposure and levels of l-carnitine and fatty acids in fish and dolphins from Galveston Bay and the northern Gulf of Mexico, finding higher PFOS levels in these organisms.
- Results indicated that l-carnitine is a more effective biomarker for PFOS exposure than fatty acids, as significant correlations between PFOS levels and carnitine were observed, which could indicate possible health issues like dyslipidemia.
Background/aims: To characterise the ocular manifestations of Williams-Beuren syndrome (WBS) and compare these to patients with isolated elastin mediated supravalvular aortic stenosis (SVAS).
Methods: Fifty-seven patients with a diagnosis of WBS and five with SVAS underwent comprehensive ophthalmic evaluation at the National Institutes of Health from 2017 to 2020, including best-corrected visual acuity, slit-lamp biomicroscopy, optical biometry, dilated fundus examination, optical coherence tomography and colour fundus imaging.
Results: Mean age of the 57 WBS patients was 20.
The use of aqueous film forming foams (AFFFs) as fire retardants is an critical point-source for per- and polyfluoroalkyl substances (PFASs) pollution into the aquatic environment. This study investigated PFASs pollution in the surface waters and biota (shellfish and fish) of Galveston Bay, following AFFFs use to extinguish a petrochemical fire (March 17th to 20th, 2019) of oil storage tanks at the International Terminals Company (ITC) in Deer Park (Houston, TX). The levels of up to twelve EPA priority PFASs were measured in surface waters and biota from March-November 2019.
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- - Usher syndrome is characterized by hearing loss, rod-cone dystrophy, and often vestibular dysfunction, with three clinical subtypes identified since the late 1970s.
- - Recent genetic studies have uncovered several associated genes and have documented "atypical" presentations of Usher syndrome that diverge from the classic symptoms.
- - The manuscript reviews the molecular causes of Usher syndrome, noting the variability in clinical presentations, and suggests guidelines for a clearer naming system for these atypical cases.
The diagnosis of a heritable (Mendelian) eye condition can have a significant impact on patients and their families. Although a diverse group of conditions, many Mendelian eye conditions are early-onset, untreatable, progressive, and result in significant visual disability. To increase understanding of the challenges faced by this population, we review studies describing the psychosocial impacts of Mendelian eye conditions.
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