Publications by authors named "R Schinner"
Article Synopsis
- Menière's disease (MD) is a complex condition linked to various factors, and this study focused on assessing differences in cranial nerves using advanced MRI techniques.
- Researchers examined morphometric changes in the VII and VIII cranial nerves of 53 MD patients by comparing the affected and unaffected sides, as well as analyzing symptom duration.
- The findings revealed no significant differences in nerve morphology between affected and unaffected sides, suggesting that early disease processes may occur before symptoms appear, and the imaging technique used was effective compared to traditional methods.
Article Synopsis
- Researchers studied how mild SARS-CoV-2 infections during pregnancy affect fetal lung growth, especially during the omicron phase of the pandemic.
- They used MRI to check the lung volumes of 24 pregnancies and found no significant differences compared to normal values.
- This study shows that mild SARS-CoV-2 infections don't harm fetal lung development like earlier variants did, possibly due to the benefits of vaccination or prior infections.
Background: The aim of the study was to assess the role of diffusion-weighted imaging (DWI) to evaluate treatment response in patients with liver metastases of colorectal cancer.
Patients And Methods: In this retrospective, observational cohort study, we included 19 patients with 18 responding metastases (R-Mets; follow-up at least one year) and 11 non-responding metastases (NR-Mets; local tumor recurrence within one year) who were treated with high-dose-rate brachytherapy (HDR-BT) and underwent pre- and post-interventional MRI. DWI (qualitatively, mean apparent diffusion coefficient [ADCmean], ADCmin, intraindividual change of ADCmean and ADCmin) were evaluated and compared between pre-interventional MRI, first follow-up after 3 months and second follow-up at the time of the local tumor recurrence (in NR-Mets, mean: 284 ± 122 d) or after 12 months (in R-Mets, mean: 387+/-64 d).
Introduction: Conventional morphologic and volumetric assessment of treatment response is not suitable for adequately assessing responses to targeted cancer therapy. The aim of this study was to evaluate changes in tumor composition after targeted therapy in murine models of breast cancer with differing degrees of malignancy via non-invasive magnetic resonance imaging (MRI).
Materials And Methods: Mice bearing highly malignant 4T1 tumors or low malignant 67NR tumors were treated with either a combination of two immune checkpoint inhibitors (ICI, anti-PD1 and anti-CTLA-4) or the multi-tyrosine kinase inhibitor sorafenib, following experiments with macrophage-depleting clodronate-loaded liposomes and vessel-stabilizing angiopoietin-1.
Purpose: The aim of this study was to compare the diagnostic performance of different sets of MR sequences in detecting extrahepatic disease of NETs on routine liver magnetic resonance imaging (MRI).
Method: One hundred twenty-seven patients with NETs with and without hepatic and extrahepatic metastases who underwent liver MRI and SSTR-PET/CT were retrospectively analyzed. Two radiologists evaluated in consensus in four sessions: (1) non-contrast T1w+T2w (NC), (2) NC+DWI, (3) NC+ contrast-enhanced T1w (CE), and (4) NC+DWI+CE the presence and number of metastases (lymph nodes, bone, peritoneal surface, lung base, and abdominal organ).