Publications by authors named "R Schiaffini"
Diabetic peripheral polyneuropathy (DPN) is the most common cause for diabetic foot complications, including diabetic ulcers, Charcot arthropathy, and lower limb amputations. Spinal Cord Stimulation (SCS) is a safe and effective treatment used for pain reduction in neuropathic/nociceptive pain conditions; the most common stimulation modalities used for the management of painful diabetic neuropathy were conventional paresthesia-based and high-frequency SCS, which stimulate the A beta fibers in the dorsal column of the spinal cord. Differential Target Multiplexed (DTM) SCS is a novel paresthesia-free stimulation technique targeting the supportive glial cells in the nervous system, modulating glial cells and neurons with a rebalance of their interactions.
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- * Hypoglycemia continues to be a major concern for those using insulin therapy, prompting the need for evidence-based recommendations for its recognition, treatment, and management among pediatric diabetologists.
- * The guidelines suggest raising blood glucose levels above 70 mg/dL using oral glucose, with specific dosages tailored for different treatment settings, and they include practical flow charts to assist in clinical decision-making, aiming for a global applicability.
Background: Tight glycemic control is essential for the normal growth and development of preschool children. The aim of our study was to evaluate the impact of advanced hybrid closed loop (AHCL) systems in a real-life setting in children younger than 6 years.
Methods: We conducted a two-center prospective study.
Article Synopsis
- Early and tight glycaemic control is essential for preventing long-term complications in Type 1 Diabetes (T1D), and this study aimed to evaluate glucose metrics, specifically Time In Tight Range (TITR), in children and adolescents.
- Conducted in a single centre with 534 participants, the study compared four treatment methods: multiple daily injections (MDI) with various types of glucose monitoring, and advanced hybrid closed-loop (AHCL) systems, analyzing their effectiveness on glucose levels.
- Results showed that the AHCL group achieved significantly better Time In Range (TIR) and Time In Tight Range (TITR) compared to the other groups, suggesting that automated insulin delivery systems could substantially enhance glycaemic control
Are the variations in ECG morphology associated to different blood glucose levels? implications for non-invasive glucose monitoring for T1D paediatric patients.
Diabetes Res Clin Pract
June 2024
Aims: Recent clinical trials and real-world studies highlighted those variations in ECG waveforms and HRV recurrently occurred during hypoglycemic and hyperglycemic events in patients with diabetes. However, while several studies have been carried out for adult age, there is lack of evidence for paediatric patients. The main aim of the study is to identify the correlations of variations in ECG Morphology waveforms with blood glucose levels in a paediatric population.
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