Publications by authors named "R Sanchez Sanchez"
Background/aims: Pediatric patients with suspected gastroparesis often undergo antroduodenal manometry (ADM) and gastric emptying scintigraphy (GES) for diagnostic purposes. However, it is unknown if delayed gastric emptying (DGE) correlates with manometric findings. This study evaluates whether ADM parameters differ between normal and abnormal GES in pediatric patients.
View Article and Find Full Text PDFAdult B-cell acute lymphoblastic leukemia (B-ALL) is characterized by genetic heterogeneity and a high relapse rate, affecting over 40% of adults. However, the mechanisms leading to relapse in adults are poorly understood. Forty-four adult B-ALL patients were studied at both diagnosis and relapse by next-generation sequencing (NGS).
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- High-risk non-muscle-invasive bladder cancer (NMIBC) has high rates of recurrence and progression, and there's a need to better understand the tumor microenvironment (TME) for identifying treatment outcome biomarkers.
- Researchers analyzed TME components and PD-L1 expression in 73 NMIBC patients, finding significant changes in tissue compared to non-tumoral samples, including increased cancer-associated fibroblasts and altered immune cell distributions.
- The study identified myofibroblasts (myoCAFs) and M2-like macrophages as particularly significant in high-grade NMIBC, with myoCAFs correlating to higher rates of cancer progression and recurrence, providing insights for future prognostic markers.
Daily adherence to WHO recommended physical activity guidelines has multiple health benefits in children and adolescents. Limited data from low and middle-income countries are available regarding adherence to WHO physical activity recommendations. This study aims to objectively measure physical activity intensities and explore associations with sociodemographic and anthropometric factors related to nonadherence to the WHO minimum physical activity recommendations.
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