Outcomes of Elderly Patients on Direct Oral Anticoagulants (DOACs) Versus Warfarin After Traumatic Brain Injury.

Background: Although evidence supports the improved safety profile of direct oral anticoagulants (DOACs) over warfarin (WF), outcomes among elderly traumatic brain injury (TBI) patients on this regimen remain unclear. This study describes the association between anticoagulation status (DOAC vs. WF use) and the rates of occurrence of intracranial hemorrhage (ICH), hematoma progression, need for surgical intervention and mortality in elderly TBI cases.

Red Blood Cell Transfusion Practices.

Context.—: Opportunities to improve transfusion safety occur at lower hemoglobin (Hgb) thresholds and single-unit transfusions. Efforts to improve compliance with transfusion guidelines and single-unit transfusion practices reduce transfusions and lead to improved outcomes.

Evaluation of the Clinical Impact of a Smartphone Application for Cataract Detection.

Background Approximately 10 million people in India suffer from bilateral blindness, with cataracts accounting for roughly 70% of these cases. However, there is a severe scarcity of ophthalmologists in India (12,000 across the country), which makes routine cataract screening very difficult, particularly in rural areas. To tackle this problem, we investigated the use of an artificial intelligence (AI)-based application for cataract screening at All India Institute of Medical Sciences (AIIMS), Bibinagar, that can be used by nursing officers and other healthcare professionals as a primary screening tool.

A Framework for Interpretability in Machine Learning for Medical Imaging.

Interpretability for machine learning models in medical imaging (MLMI) is an important direction of research. However, there is a general sense of murkiness in what interpretability means. Why does the need for interpretability in MLMI arise? What goals does one actually seek to address when interpretability is needed? To answer these questions, we identify a need to formalize the goals and elements of interpretability in MLMI.

Assessment of Oculomotor Functions as a Biomarker in Mild Traumatic Brain Injury.

Mild traumatic brain injury (mTBI), or concussion, is a major public health problem, and ambiguity still exists regarding its diagnosis. While functional magnetic resonance imaging (fMRI) has been identified as a helpful screening tool for concussion, its limited accessibility in clinical or field settings necessitates a more efficient alternative. Oculomotor function deficit is an often-reported pathology in mTBI.