Publications by authors named "R Saiz-Diaz"
Article Synopsis
- - Normal and benign epileptiform variants present a diagnostic challenge in electroencephalogram (EEG) interpretation, requiring specialists' experience to accurately evaluate them.
- - Many of these findings are considered non-pathological and can lead to misdiagnosis and unnecessary treatments if over-interpreted.
- - The review will focus on the characteristics, prevalence, and updated clinical significance of key benign epileptiform variants in relation to epilepsy.
Objective: This study investigated early, real-world outcomes with cenobamate (CNB) in a large series of patients with highly drug-resistant epilepsy within a Spanish Expanded Access Program (EAP).
Method: This was a multicenter, retrospective, observational study in 14 hospitals. Inclusion criteria were age ≥18 years, focal seizures, and EAP authorization.
Aim: To evaluate the effectiveness and tolerability of cannabidiol (CBD) in patients with developmental and epileptic encephalopathies, including Dravet syndrome (DS), and Lennox-Gastaut syndrome (LGS), in a Spanish Expanded Access Program (EAP).
Methods: This was a multicenter, retrospective, observational study of patients treated with purified CBD in 14 hospitals across Spain. Patients with (1) written informed consent and (2) at least 6 months follow-up before the closure of the database were included.