Publications by authors named "R Sacco"

The ocean is facing many anthropogenic stressors caused from both pollution and climate change. These stressors are significantly impacting and changing the ocean's ecosystem, and as such, methods must continually be developed that can improve our ability to monitor the health of marine life. For cetaceans, the current practice for health assessments of individuals requires live capture and release, which is expensive, usually stressful, and for larger species impractical.

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  • * Conducted on 65 CD patients, the findings showed that 32 exhibited the bright luminal sign, which demonstrated high sensitivity (90%) and specificity (85%) in identifying fibrotic strictures when compared with other imaging techniques.
  • * The results suggest that DWI hyperintensity could serve as a non-invasive indicator for detecting severe intestinal fibrosis, aiding in early diagnosis and potentially preventing complications. However, further research with larger
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  • - This study analyzes natural gas markets in Brazil, Mexico, Colombia, Argentina, and India from 2000 to 2020 using historical data and Porter's Five Forces to understand industry dynamics across different sectors.
  • - It highlights Brazil's struggles with domestic production growth despite regulatory reforms and infrastructure efforts, indicating ongoing challenges in realizing sectoral expansion.
  • - The research stresses the importance of policy improvements for better investment alignment and offers recommendations for stakeholders to navigate competitive landscapes and address potential market bottlenecks.
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Prolonged treatment with anti-CD20 antibodies can lead to hypogammaglobulinemia and increased infection risk in multiple sclerosis (MS). We investigated switch from anti-CD20 to cladribine as a strategy to prevent immunoglobulin reduction while preserving efficacy. We prospectively analysed serum IgG, IgM, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) in 44 patients, 14 who were switched from anti-CD20 to cladribine and 30 continuing anti-CD20.

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  • Latin Americans are often overlooked in genetic studies, which can widen gaps in personalized medicine due to the challenges of accessing genetic data and consent processes.
  • The Genetics of Latin American Diversity (GLAD) Project compiles genetic information from over 53,000 individuals across various regions to explore diverse ancestry and gene flow in the Americas.
  • GLAD includes a tool called GLAD-match to align external genetic samples with its database while protecting individual privacy, thus supporting more inclusive genomic research and enhancing personalized medicine for Latin Americans.
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